Yes, Nuendo can do that in that case using Reconform.
When you have a multitrack recording in the most “musical” sense, meaning they were just a bunch of tracks in the same session that were recorded simultaneously, they will be in perfect sync and more than likely have the timestamps. That’s all you need.
Since it seems to be various different takes, you can’t start with a change EDL. First you export an EDL of one of the unedited tracks, then you export an EDL of the edited track. Generate the Change EDL from those and use that to reconform all your unedited tracks.
The Reconform per se doesn’t need sync between files at all. It will just chop the entire timeline block by block and take whatever is there and copy it to the new location. It doesn’t care if it is a long clip from production audio or thousands of foley edits. If it sits in TC XX:XX:XX:XX it will be moved to TC YY:YY:YY:YY and that’s it.
Alternatively, in your case specifically and in a time-consuming - but perhaps more straightforward - way, you can use the “shift+drag” alternative to substitute the edited tracks audio with the unedited ones.
Save a new version of your project. In this new version, leave only the edited track. Now, open you audio folder and shift+drag each unedited audio clip to their appropriate event. Nuendo will ask you if you want to replace all occurrences of that clip, you say yes. Now you have the previously unedited audio replacing the edited one perfectly (since they were all in perfect sync to begin with). You’ll have to do that of each one of the separate takes, since they reference different audio files.
Now you go to File> Import> Tracks From Project and import the edited tracks again, from that first project. Do the shift+drag again with the next unedited audio clips, take by take. Rinse and repeat until you have replaced all the tracks from your multitrack. Now re-import the edited track one final time and you’ll have your whole audio edited according to that guide track.
EDIT: Oh! I forgot one factor. For this to work without issues with TC from the editor, you must ask for the AAF without handles, meaning, referencing WHOLE audio files. This way you are sure that the files that come from the edit are the same length as your unedited ones.