Problem with connecting to Cubase 9 VST plug-in Gitar rig 5.

I use Steinberg UR12. The Guitar rig worked fine before installing Cubase. After installation, on any preset appeared a strong whistle instead of sound.
When the right output channel is turned off, the whistling disappears. But then the sound is audible only in the left dynamics. This is a problem when you turn on Guitar rig standalone, and when you connect VST to Cubase. Has anyone had this situation? What to do in this case? Help me please!

Maybe you have created a feedback loop.
Make sure loopback is turned off on the UR22 control panel.