Project intermittently skips when new virtual instrument starts

Intermittently when I open a previously created project, it runs fine until a new virtual instrument kicks in for the first time in the project. The entire project audio drops out along with a screen flicker for a fraction of a second and then continues. If I rewind and start again it will play fine through the time the where the project previously glitched. Doesn’t seem to be the same instrument. Is there some sort of buffer setting I’m missing?


Increase your Audio Device’s Buffer Size, please.