I track and edit / mix using different audio devices, and I’m sure that others do the same.
One of the annoyances I run into with Cubase is that it doesn’t remember connection routing when switching devices. So, if I start up Cubase with the audio device I used for tracking selected, and then I switch to the audio device I use for mixing, I have to re-do all of my connection routing.
And if I save that project while working on editing or mixing, and then need to record something again (happens all the time), I switch to the audio device I use for tracking and have to re-configure all my connection routing for that audio device.
Having connection routing remember per audio device would be a big improvement to the workflow.