Sample Rate Converters: Do DAWs actually "sound different"?

Have to remember, that while one can choose to do an external SPC when importing existing material, or rendering a final mix, some scenarios may be more difficult.

One such scenario is running a project at higher than 44.1k and playing, in real-time, samples that were recorded at 44.1k, such as EastWest libraries. These will be up-converted on-the-fly by Cubase.

Here is a great video on aliasing and yes it is audible as he proves. UNDERSTANDING HARMONICS & ALIASING || How to visualise plugin harmonics & how to test audio aliasing - YouTube