Something weird happening with the plugins

Screenshot 2024-09-16 131608

This is a Cubase 13 project. I am not being able to use any of the deselected plugins which are lighter in colour, for instance “CHOW” from the ELG Floaty GR track. When I click on it, absolutely nothing happens. When I select it for the first time, it shows up and immediately becomes unclickable. The plugin window opens and I can change the parameters, but it has no effect. I can’t turn it on or off. It just stays the lighter colour. The darker coloured plugins, like Valhalla from the same track, is working fine. Any idea why this is happening. Cubase 10 had no such issues!

Do you have Constrain Delay Compensation turned on by chance?

Yes, that was it! Thank you so much.