Sound of UR44 cracks

The sound of my UR44 cracks on the left side. At first I thought it was the monitor speaker or a cable, but it also cracks on my headphone. Anyone had this too? What could be the problem and solution for this?

I had crackling issues using the built in USB ports on the mainboard. Any chance you can test it on a different computer?
I ended up getting a PCI USB card extra for the UR device.