I am a big fan of the control room feature in Cubase and Nuendo that allows me to run different insert plugin chains for each configured output. This allows me to run my favorite binaural simulation plugin (Toneboosters Isone) on my headphones while I keep clean my main speaker output.
It would be nice if there was an ability to facilitate insert plugins for each speaker set configuration.
Just my $0.02
–Stefanos