Studio 4 Freezing

Intel Core 2 Duo
Pod X3
Edirol UA-25

When I use the Edirol everything is fine but when I use Pod X3 as my ASIO Driver I get about 4 minutes of magic then Cubase freezes up. I need to reboot to get everything running again. Tried changing settings on Line 6 Tools but no joy so far.
I do believe there is an expert out there that can say have you tried ooffing the digglebok or similar and it will be fixed. I am not adverse to feeling stupid when the obvious is pointed out.