System Settings Loses all Entries - Desktop is Different. Help!

I’ve been looking all over the net but nothing is helping. So I figured I would try out all the brilliant Mac users here.

My system settings has suddenly lost all the entries. Only thing in there now is general and something about Code. I have booted into Safe Mode, restored from a Time Machine backup, reinstalled Mac OS, ran first aid, etc. Nothing is helping. I can run my music programs like Nuendo and Cubase thank goodness. I’ve never run into anything like this. I thought using Time Machine would fix anything but nope. Any help would be greatly appreciated.

Sounds like your operating system drive has a bad error in it. I’d replace the system drive and reinstall everything when you have the time to do so.

So sorry you’re experiencing that.