My Key Signature is B Major with C# F# D# A# G#.
The notes B to C are half step
and the notes E to F are also a half step.
The problem is on a 6 string guitar.
In the 6-string tuning of low to high, DADEAD.
On fret one, with E open on the third string.
The first fretted note should be F, not E#.
I hope this works and Thank you,
G L