bug report, Cubase 8.0.35.
Create an Instrument Track; add a send to a new FX Track; and put Lexicon PCM Native as an insert on the FX Track.
Bypass the Lexicon PCM Native. Now the audio on the Instrument Track and the audio on the FX Track are out of sync. To confirm that they’re out of sync, invert the phase of the FX Track, and verify that it’s not nulling with the Instrument Track. This synchronization problem persists during Export Audio Mixdown.
Next, Deactivate Lexicon PCM Native. Now on the Instrument Track and the audio on the FX Track are synchronized correctly: The FX Track nulls with the Instrument Track (assuming the phase is still inverted on the FX Track).