UR22 possibly causing all sound on PC to cut out

I’ve been having an issue whereby all the sound on my PC will cut out. It doesn’t matter what I’m doing, it will eventually happen. If I unplug the UR22 from the USB port and then immediately plug it back in again the sound will come return.

I’m running Windows 10. Device manager says everything is fine, even when the sound cuts out. I do wonder if it’s the OS glitching out because I’m also having issues with the start button and task bar not working.