UR22mk2 Creates high pitch wining sound when pc is turned on

:question: Hi,
When i turn on my pc the UR22 mk2 creates a high pitch wining sound thru my active studio monitors, even if the audio interface is switched off.
If i disconect the Usb cabel then its ok. It appears the USB audio device is creating infearance with my speakers.
I have the latest driver installed under win10 64bit.

Any ideas whats going on?