Here is what happens . . .
Created a project. Over the course of working with the project create 19 instances of Kontakt.
Saved project. Exited Cubase (6.5). Shut down. Started up next day.
Load project. It loads instruments. Finally brings up the rest of the screen (control room, vst instruments, etc.)
Crash. (no crash dump either)
If I remove a few of the instances, it starts up fine. Tried with my older audio interface (Alesis Mastercontrol) and it works fine with no issues on load. It also starts up fine without the UR28M on.
Faulting application name: Cubase6.exe, version: 18.104.22.168, time stamp: 0x50375a24
Faulting module name: ntdll.dll, version: 6.1.7601.17725, time stamp: 0x4ec4aa8e
Exception code: 0xc0000374
Fault offset: 0x00000000000c40f2
Faulting process id: 0x13b8
Faulting application start time: 0x01cdc5c452cc5287
Faulting application path: D:\Program Files\Steinberg\Cubase 6\Cubase6.exe
Faulting module path: C:\Windows\SYSTEM32\ntdll.dll
Report Id: da0dc201-31b7-11e2-b0a2-001fbc0db370