VSTi - No sound from Output 1/2

Hi, I’ve been having a strange problem since updating to Cubase 10.5.12. The ‘main’ output of any rack VSTi I have loaded doesn’t produce any sound in Cubase. The other outputs all work fine, and when you go into the VSTi itself, it seems to be generating sound on that channel no problem… It’s left me really baffled and I’m wondering if it’s a new bug.

Has anyone else had this issue at all?

I’m running on an Gigabyte Aero 15X, spec below:

Windows 10 Pro - GIGABYTE recommends Windows 10 Pro for business.
Windows 10 Home
NVIDIA® GeForce® GTX 1070 GDDR5 8GB with Max-Q design
8th Gen Intel® Core™ i7-8750H Processor
World’s First Full HD 144Hz IPS Panel with Thin Bezel Design
4K UHD IPS Adobe RGB 100% Panel (Optional)
5mm Thin Bezel Design: Experience True Visual Immersion
X-Rite™ Pantone® Certified Display
94Wh Huge Battery Capacity for 10+ Hours Productivity
Thunderbolt™ 3, mini DP 1.4, HDMI 2.0: UHD 4K 60Hz Output
UHS-II Card Reader: 12X Faster Transfer Speed
Blazing-fast M.2 PCIe Gen.3 X4 SSD: Reach 2000MB/s (Optional)
DDR4 2666MHz: Next Generation Memory
GIGABYTE Fusion Keyboard: 16.7M Colors Per-key RGB Backlight
Unique Aesthetics with Aluminum Robust Body
CNC Chassis: Brings Back the Art of Crafting
Dolby Atmos: Moving Audio


What Audio Device do you use? Do you have the latest ASIO driver installed, please? Could you try to increase the Buffer Size, please?

In this instance I was using the Steinberg Generic Low Latency driver with the onboard laptop sound in this situation, when at home I usually use the Steinberg UR824. I’ve never had this problem before…


Do I understand you right it doesn’t work even while using UR824? Could you double-check the routing, please?

In which Cubase version were these projects created originally, please? Could you share one is the project (or at least a snipped of it) here, please?