This huge resolution was never tested. And i currently dont have the hardware to test it. Is is important that you stretch the whole screen over two monitors? Usually, people use 2 monitors as independent screens. And this works ok.
Work since years with a two monitor setup with stretched desktop.
In Nuendo, left side ist the arrangement and on the right side the mixers, channel edit, VSTi’s … in Wlab, left side is waveview or the montage and on the right side the meters, filemanager … My windows are in min status, so ther are no problems with open Nuendo or WLab.
I like my setup, because I’m near 50 years old and the big screens a good for my eyes