Simply use your ears and Use the one which sounds best.
Unless of course your trying to achieve a specific technical specification for the audio, such as EBU R128 standards, in that case which ever one sounds best and gets you where you need to be!
I have found with my limited experience with audio, (there are many other more experienced then me on the forum - I am here to learn too!)
that there is no right or wrong tool or method, but each different plug in will have its own sound, and will have been designed for a purpose. However newer plug ins tend to do what older ones do and more, often with better processing and transparency. Sometimes the older plug in is left available for backwards compatibility. I tend to stick to using the Master Rig for my wave lab processing needs. Imo its replaced most of the individual stock plugins, for general usage.
For you needs I would surjest getting to know master rig too, It really is a amazing tool, and can sound as clean or a coloured as you like it. Its very flexible been modular. Its covered in good detail in the help documents, and in some videos.
Hope I have helped a bit.