My display resolution is 3840x1600, I love the fact that it can effectively display my projects without having to resort to multiple monitors.
The problem is that not all plugins support high resolution monitors.
Even the most essential plugins: UAD, NI, Brainworx, Waves, etc… have a limited notion of display capacity.
At 150% magnification, Windows Magnifier works pretty much perfectly for every plugin that is limited by the display resolution.
This might be a good tool to be aware of on Windows platforms.