Hi, probably a silly question but did you test playback?
I see a similar picture to you and almost on the exact same device (my Mac is late2015 and UR22mkII)
i notice that your device isn’t showing as ‘USB’ type?
I see the following
notice 2 x devices one of type USB - weird…
I can play through Mac if i select the USB as mac output but as soon as i try and open cubase or launch the preferences pane from within settings the USB one disappears and although i can select the non USB one when opening cubase i can’t hear any sound from it.
This is what i see when attempting to start cubase
then when i try and select the option steinberg ur22mkII (the non (2) option)
hmm can’t seem to add another attachment here but i get a pop up stating
“The audio driver could not be loaded. Please make sure your audio hardware is connected correctly to your computer.”
If i select option Steinberg UR22mkII (2) cubase opens but i get no sound - nothing registering in the meter’s - if i change asio to built in audio meters come alive and sound is heard through mac speakeers…
Cubase Artist 10
yamaha usb 1.10.5 (although shows as 1.10.4 via mac system report)
OSX 10.15.1
I notice your screen shot of System>Sounds the device doesn’t show type? which as stated above is the same state i get when i try launch cubase or the preference pane (yamaha usb driver control panel)