Best Setup Synario

Well Here Goes My Second Post and Hoping for Help…

My Equipment :
Zoom R 16 - Delta 1010LT - Big NOB Studio Control system- HeadAmp Pro - Tannoy Powered Monitors-
Pioneer Stereo Amp and Speakers - Creative Labs Audigy 2 SounCard- Quad Core AMD Phenom II X 4 -820 2.8 GHZ

Computer W / Win 7 Ultimate 64 BIT and CUBASE 6 … Ok and some other Stuff you Know LCD Moniters , Cables , Keyboards , Mikes Etc.

So You Know I Used the R16 and LE4 (cubase) for about a year before I Upgraded Like a Mad Man to Whats Above,

My Question is and I am Hopeing I get some responces based on my Equipment …
What Is the Best DAW Setup to best Utalize First What I Have ,and Use Not Only To Record , But To Listen to CD’s Mp3,s etc , based Music in my Computer Setup , and Not Be Plugging or Unplugging Wiring …
Please Let Me Know Your Thoughts /Ideas’s …


Thanks
BUG