If I open a project in N8.1.10, check that the Input and Output settings are correctly loaded in Devices/VST Connections, and then save the project; when the project is opened in N10.1.0 the Input & Output settings are not loaded. If I then load the correct Input and Output presets and save the project in N10, when I open the project in N8 again the Input and Output setting are no longer loaded! - and so on, round and round.
N8 and N10 are both auto-loading the same project when they are launched.
Note: Similar posted in N10.