In the last half year Windows 10 got updates that Protect More and More Locations on your computer.
These to me where really bad updates, because like Outlook i had placed my emails PST file in one of those protected dirs (where Microsoft placed them by installation). The wierd thing was their own product Outlook 2013, did not even work anymore. I could not even get emails.
Why i say this ? Well cubase and halion tend with medaibay and scanning of files to reach protected dirs. What before where none protected dirs, suddenly by updates microsoft changes the status of a dir into archive or protected. (system).
That can a big problem for programs you are used to install, but now suddenly you can / but with errors.
Also Mircrosoft tries each time to make Windows 10 more secure (alltough temselves are like NSA spy on you anyway), this can be blocking or intruding with install.
I use Windows Repair from Tweaking.com not at version 4, and helped me many times to Fix Windows 10 issues i had afther installing updates from Microsoft (like the message window not working completely, and also one time i could not even start any program), it fixed must bugs and sets a good Windows and repairs it where needed.
Also i use Norton Uttilities and Norton as a Virus Scanner.