Did you get any resolution to this problem ?
I too have the same problem it seems after updating Windows 10 recently.
On trying to start up Cubase (8.5) I get the usual Cubase symbol in a small window in the centre of the screen.
Then within a few seconds, another small window opens which says
“please wait while Windows configures Yamaha Steinberg USB driver”
Then, a couple of seconds later another small window opens which says
“Windows installer preparing to install”.
That is where the loading of Cubase stops.
If I press the “cancel” button on the window, the cursor just goes into the spinning “doing something” state, but just stays like that.
Then have to use Task Manager to close it down.
I also have Reason loaded on my PC (which I have never used) and this also has exactly the same issue if I try to load it, so I think not a specific Cubase issue; more of a Windows compatibility issue ??
I have checked the driver for the Steinberg and the message reads “windows has determined that the best driver for this device is already installed”
Looking on the “Events” tab when checking the driver, the three lines of info shown read:
Device not migrated
Maybe the third line is a clue ??
The message also states “device is working properly”
I also have Spotify on my PC which plays through the Steinberg U242 and then into a pair of studio monitors.
This works perfectly well.
The volume control on the U242 controls the volume of the Spotify track being played as normal, so it seems the U242 works fine until I try to load Cubase (or indeed Reason).
I also have Audacity loaded on the PC which I used to use before I bought Cubase.
This still seems to work OK via the U242.
I’ll also try to copy this and post as a new post in case yours got “lost” in the midst of time !!
Hope you resolved it.