Groove Agent 5 Global Pattern Pad Settings

I’m just getting my head round Global Pad Settings when using multiple agents in Groove Agent 5 by reading the manual. When I add a second agent I get the message “Loading the kit will overwrite the global Pattern Pad settings. To avoid this you can lock them” There is the option to “lock settings” or “overwrite settings.”. What’s the difference and which scenarios might you lock them or overwrite them?