For the OP, yes I would either start in safe mode or trash preferences.
Martin, I have a few questions about this I have been wondering for a while.
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Considering the different options in safe mode, is one of those options identical as if you would have deleted everything inside the Cubase folder, meaning trashing preferences, then re-start Cubase to re-build?
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More importantly, if I was to do the trashing of preferences instead of using safe mode, I have always felt that before trashing preferences, I should first “hide” by re-naming any prior Cubase versions…for example if I wanted to trash C10.5 preferences, first re-name or “hide” C10. The reason for doing this is to assure myself that absolutely nothing is being carried over from C10 to C10.5 when I re-build or re-start C10.5. Am I being paranoid?
I think we both know the automatic transfer of key commands from one version to another doesn’t work. Therefore I always manually transfer those preferences.