When I tested the Nektar Panorama CS12, I noticed one unpleasant thing about its operation. There is also a Shift button on this device, which you have to press simultaneously with another button for many functions. However, the Shift button is so far away from the other buttons that you need BOTH HANDS to perform theese functions. That really annoyed me. 
The FaderPort is much more comfortable because I can operate the whole device with only just ONE HAND. 