For 2020 this is one of the best systems for audio, if not the best.
Everything worked right out of the box, and great for Nuendo 10.3.
I was debating between Intel and AMD for the last year, and I saw a few unhappy cases
on the AMD camp, so I abandoned the Ryzen 3950X and chose the Intel i9 10900k build instead.
After several battles with Nuendo 10.3 in Windows 7, which is no longer supported by Steinberg,
the new Intel i9 10 series system is solid in my studio, and I am relaxed, instead of “Ctrl Save” every minute
because of crashes. So far not a single crash after 2 studio sessions of test runs.
Intel i9 10900k
Evo 970 Pro NVMe M.2 1 TB
Z490 motherboard Asus Maximus XII Hero Wi-Fi
64GB DDR4 RAM 3200MHz Corsair Vengeance LPX
Noctua Cooler HD15 double fan
Corsair case Carbide 678C
4 Noctua A14 iPPC-3000 PWM fans
NVIDIA GTX 760 2GB RAM- older card but works fine for audio
Power supply EVGA 1200 Watts 80+ Platinum (overkill but I plan a GPU card upgrade)
Triple monitors Asus 32"
UAD 1 PCI bridged with StarTech PCI Express to PCI card
RME HDSP Hammerfall 52 Channels ADAT, bridged with StarTech PCI Express to PCI card
You can barely hear if system is on or off because of the Noctua fans slow RPM.
Full system power at idle, except monitors- 130 Watts. Maximum draw 300 Watts.
I hope this helps anyone planning a build.
EDIT: RAM Cache III, a feature in the Asus Maximus XII motherboard, creates a RAM cache disk
(mine is set at 4GB) that allows Nuendo 10.3 to start much faster. Interesting and exciting.