Just had the same problem as the op described, at first I had no Roaming\Softube folder, so I uninstalled all Softube products, including Softube Central. After reinstalling I still had the same problem but the Roaming folder was present with the Global Settings.txt. After changing “true” to “false” all the plugins and instruments worked perfectly, however, the preset collection window was blank, the preset drop down menu on the main GUI worked fine though.
I then changed “false” back to “true” on the Global Settings doc and now everything appears to be perfect, including the preset window, but tbf the preset window is not absolutely necessary, just nice to have sometimes.
Anyway, thanks very much for your advice.
Have the same problem here, but it seems to be somewhat random. Sometimes sessions load just fine, sometimes they don’t. It seems to affect certain .npr/.cpr files, and not others, i.e. some saves/versions of the same project open just fine, while others not.
What I have found as a workaround for the moment is to have the Softube Console 1 OSD app running when first opening up Nuendo/Cubase, and when getting to the “hub”, just before loading the problematic session file, I close down the Softube Console 1 OSD app (right click on taskbar icon on Windows, and select Quit), then load the project file and it opens like a charm.
Once the session all loaded up, I restart the Softube Console 1 OSD app, and it starts up and picks up the session perfectly 
Anyway, lets hope for a quick solution to this, as it is quite problematic!
Did you try the previous “fix”? Worked for me
Disabling OpenGL doesn’t work for me. Still freezing Cubase.
I just had this problem with Softtube 72 synth and following the instructions updating “Softube Global Settings.txt” as mentioned above fixed it!
Just create the Folder -Softube- in C:\Users\AppData\Roaming and put the txt as described by Nilsson. In my case the folder Softube was missing.
I was fine with Softube until this month April 2024. Not sure which update caused the problem. Just noticed it yesterday. It was fine last week. I guess I will try some things above.
Existing Softubes plugins work. I only have lock-out/ freeze-up when I try to add a plugin to a track.
4/20/2024 Update: Setting OpenGl to ‘False’ did not fix the problem
I think I will blame MS Windows. It updated on 4/12/24 and I’ve only had problems with Softube the last few days.
Also,TFD escalating due to Mercury retrograde 4/1-4/24
TFD= Technology Fails Daily
Softube has fixed my problem with the latest update 2.5.83
Change log for 2.5.83 (Released on April 29th, 2024)
All products:
• Fixed an issue where a corrupt Preset Collection settings file would cause plug-ins to crash on Windows.
(Also Mercury is now direct)
I’m demoing Amp Room, the Marshall collection. And here’s a quirk, when using the Amp Room plug-in, Asio Guard usage is bottomed out, zero use, and Peak goes through the roof, almost 75% and jumps into the red with pops and crackle.
On the other hand, using the amps’ plug-ins separately (e.g. loading a bluesbreaker instance instead of the amp room) it seems that ASIO guard works more, and Peak usage is more manageable at about 40%.
I have tried openGL on and off, not much difference. Also had a crash that did not offer a crash log on Cubase restart.
Anyone using it right now that could tell me if there are known issues or any other stuff to do?
Hi, I have problems since october…anyone of You has the OSD panel at win startup with the write ‘designed in sweden’ that not disappear? In my old PC this write disappear immediatly, with the new win and pc it still remain. It seems that the OSD not fully loaded. I’d like to know if there are windows services needed to OSD, caused I’ve disable someone to speed up win start.
YESSSSSS many many thanx man!!! Since november I’ve tried anything to solve this issue, I’m on softube support since 3 months!!
I’ve just wrote to them to indicate your workaround for solving this issue that is a nightmare, so thanx again!!
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Hi, do You had osd problems that now are solved?
My problem still the same with new update, without workaround no work. Since october this issue is not solved again
Have You tried last version 2.5.85?
I think I’m having a related problem here…having the OSD loaded in my taskbar causes all of my VST3 plugins to have frozen GUIs in Cubase. I can get them back if I quit the OSD and restart Cubase, and if I THEN open the OSD things work fine.
anyone seeing THIS variation of the bug?
Not me so far, everything’s normal here with the new update
Yes…this bug is happen since october…and softube have not fixed again!!! Update after update is the same issue. Very disappointed to Softube
It’s been fine here (with open gl off)