No Sound with MOTU Ultralite mk5

Hello there, i’m having an issue that is preventing me to work, so i’m trying to fix it as soon as possibile.
I recently updated to Nuendo 11 to work on a Macbook Pro M1 but Nuendo doesnt play audio (and doesn’t move meters too) when is set with my MOTU Ultralite mk5.
I’m pretty sure is a Nuendo problem because the Motu works fine with Spectral Layers, Ableton Live and system sound.
Anyone have an idea how to solve this problem?

Does Nuendo have access to the microphone?

Thans for the reply, yes it does!