No sounds on note input after updating to Dorico 5.1.80

Well, compared to the default set of Preferences, the ones you’ve changed in the note input category are:

  • By default, specify pitch Before duration
  • Specify accidental, rhythm dot and articulations Before inputting note
  • By default, enable note input using the mouse is off
  • Enable note pitch and rhythmic position editing using the mouse is off

So the only thing I can suggest is to try changing those values one at a time and see which one makes it start working again.