The mouse wheel scroll is pretty much unusable – overly fast (so very limited precision) and jumpy (so visually hard to follow).
I compared with Bitwig (which has beautiful smooth scrolling). If I set up 5 measures on the screen, in Nuendo the smallest scroll wheel movement moves the screen 1 measure.
In Bitwig, the smallest scroll wheel movement moves the mouse 1/16th of a measure. Much more precise and easier to navigate.
Bitwig also responds to the mouse wheel more smoothly. In Nuendo, the screen moves in jumps, not in a smooth movement.
Similar issue with vertical scroll – the movement is too fast and jumpy to be useful – and also zoom (slightly less bad with zoom but still not great).
Curiously, if you place the cursor over the scroll bar and roll the scroll wheel, the speed is much better, about 4 times slower than when the cursor is on the screen. (But it’s still a little jumpy, not as smooth as Bitwig.) But obviously you can’t really work that way – moving your cursor to aim at the tiny scrollwheel and then moving it back to where you’re working.
Is there any chance of improving the mouse scrolling? My scroll wheel works beautifully on literally all the other programs I use except Nuendo.