Hung on, this is the resolution that an audio card can support.
I never go to 192 for recording and playback, let alone 384. Damn, the amount of data would be insane to handle.
The stuff I produce is in industry standard 48/24.
I sometimes record on a higher rate if I need better quality vocal, or quitars, but I downgrade to 48/24 as I will have deliver at this rate.
384 is obviusly better but I would be very surpised if anyone uses this rate.
If you could prove that Nuendo sounds better at 48/24, then that would intetest me.