Optimum PC config for WL11 or WL12

What do you mean by "checked for Vega driver (none) ". I had it that I had to install the driver twice. In the first step the driver deinstalled itself. You should have a Desktop context menu entry “AMD Software: Adrenaline Edition” that calls the Adrenaline Driver Settings Window.

I did, I saw no such driver installed
Here is my updated drivers in Adrenaline:

And after the installation of the latest chipset drivers too still the stuttering? Here the link again:

https://www.amd.com/en/resources/support-articles/faqs/CHIPSET-INSTALL.html

That would be a pity. In a few weeks I may be able to check if this behaviour you described is also an issue with a 6850U. That would be a real problem for me if there were any issues. I stay on windows 10 as long as possible.

You had the same problems under Windows 10?

Here the Ryzen Master screen with the better timings for my system:

I encountered yesterday a very sudden appearance of lagging behaviour in responsiveness maybe very much that what you were faced with.

Culprit: I switched from my audio ASIO-driver to the “Windows MME” driver because I had to record audio live whilst changing settings in master-section plugins. It worked for the recording. I omit the windows driver because it may resample things and may mix Audio from other sources into the output signal.

Suddenly … out of the blue … very lagging behaviour as I switched back to WaveLab that was in the background for a while.

That may had nothing to do with the graphics unit at all. ( I use a dedicated graphics card with HBM-memory. )

PS: Is there another way of live recording to record the results while using mouse and keyboard to manipulate plugin-settings in the master-section? With render, it is not possible.

Apparently, you are using an old WaveLab version (MME driver).
In more recent WaveLab version, there is this: