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There are differences, but they are pretty subtle. Pro on top, regular on bottom:

There’s even a “Minion 3” on Adobe’s site so I assume Robert Slimbach has made a few tweaks with each subsequent release.

Interesting. Definitely noticeable, although I don’t necessarily have a preference. At least there won’t seem to be any spacing changes with lyrics.

The ligatures all seem to be the same, too.