I just tried changing the sample rate and restarting the program. It plays back normally from the beginning the first time, then everything seems shifted forward in time, with only silence if I select a point later in the piece. The time position in transport and the playhead are aligned, but the sound doesn’t match. I also forget to mention that I’m working on a file created in Dorico 1.
Are you on Windows or Mac? What kind of audio hardware do you have?
I’ve encountered this, though rarely. Restarting the computer has always fixed it for me.