I dunno if this is a Cubase issue or RME issue or WL issue or Windows issue.
I’ve had the same RME 9652 for a decade. I recall using Cubase and WL4 for years and being able to go back and forth between WL and Cubase (at different sample rates) with no problem.
At some point, perhaps when I upgraded to WL7… or some version of Cubase or…? I dunno… I no longer can do this. If the Cubase CPR is at, say 48k and I open a WL audio file at 44.1, Cubase automatically gives me the dreaded “The ASIO Rate Has Changed…” and the project is messed up.
You get two choices: allow multiple sample rates or not. Either one makes the project unusable, so I end up closing Cubase and re-starting.
I -thought- the RME ‘multi-client’ could be configured to avoid this, but frankly, I’ve forgotten how to make this work. Can someone refresh my failing memory?