Presonus Audiobox 22VSL as input to Cubase 10 LE

Is it possible to use the Audiobox 22VSL in addition to my Line6 Spider V for other input (ie Mic / keyboard)?

Hi and welcome,

No, in Cubase you can use only 1 ASIO driver in a given time.

The solution would be to install ASIO4ALL and merge both Audio Device to one virtual ASIO driver.