Not sure I can explain this. With Ozone 7 (or was it 5?) active on the main bus, I was getting an unuseable amount of latency from my midi controller to any VSTi loaded. For the first time ever, I (grasping at straws), clicked the icon in the upper left toolbar (something about latency compensation…sorry, gonna rtm in a minute), and the problem went away. Initially, I tried bumping my buffer size from 256 to 512, but no dice. 256 had been working fine for years. Not saying there is a problem with Cubase 8.5 Pro or Ozone 7, but rather, likely ignorance on my part.
There is something nested deep in the Ozone preferences regarding latency compensation, but I have not gotten that far yet. If any of you have some light to share, I would be grateful. In the meantime, I’ll put on my reading glasses and revisit the documentation. It just seems strange for this to occur. Things that have changed are going from 8.0.3 to 8.5 and jumping from Ozone 5 to 7. Part of my confusion was that I was toggling back and forth between O5 and O7 on the master, comparing the results. Having both of those loaded, even with only one enabled at a time might be the culprit. Hmmm.