Wavelab has a great way of working with say 96kHz files, but connected to a 48kHz device. We use this for sound FX, which are recorded in 96, but the master device and mixing is all done at 48. In Wavelab there’s a special Resampling tab for just this purpose with it’s own plugin. It’s good to work in 96 for SFX as those sounds get processed so much oftentimes the extra extension is a safety margin to avoid artifacts.
Anyhow, maybe a simple question but is it possible to do something similar in Nuendo? That is work in a higher sampling rate (clips, recording, etc) but just downsample on the entire output for the audio device?