I always want to disable parameter-change with mousewheel to prevent accidental change of something in the mixer. But I really want to temporarily activate parameter-change with for example pressing alt/option and scrolling. That would be perfect, then you have quick and total control over any parameter-change.
But it seems impossible to set up, anybody have any ideas?
There is a key command slot available to toggling the mouse wheel behavior. Maybe that is helpful to you?
Thanks for the tip! But its to slow, I have to press the button multiple times. 
And I have to remember which mode is on.
I just want to scroll around without fear of changing anything, and press e.g Ctrl when I want to change a parameter. To me, that would be the most efficient way to work in the mixer.