Nuendo wasn’t being recognized by the Contour Shuttle app, so I made a copy of the Nuendo settings. In the Contour Shuttle app, right-click the default Nuendo settings and choose “Copy to new settings…”. Select the Nuendo app from the file list. These copied settings will now be active whenever Nuendo is in focus, and you can modify them from here.
I had to change a couple of the default assignments in both Nuendo and the Contour Shuttle app. In particular, for the jog wheel I changed the assignments to a Ctrl sequence for each direction (Ctrl-o for left and Ctrl-p for right). I did the same for each zone of the shuttle ring, also ensuring each assignment in Contour Shuttle was set to “Type Keystroke” and “Hold Down.” Works very well.