Tracks suddenly Pan to L

I’m having an issue with tracks suddenly panning almost entirely to the left without any input. This happens on brand new tracks that have no CC or any other input. It happens on Instrument Tracks and if I’m not mistaken it happened with a Rack Track (VEPro) using Kontakt on another computer.

Here’s an example. I create an instrument track using Retrologue. I play/create a midi part that triggers the sound in Retro. At some point…randomly, the sound almost entirely starts to come out of the left channel. Nothing has been touched with regards to Pan. In fact, panning the output channel all the way to the Right results in almost no sound.

I’ve checked the output controls on Retrologue and nothing has changed. The pan is C.

What in the heck am I missing and what can I do about it?