[quote=“BoydPro”]I’m purchasing/building a new workstation computer and was hoping to get some practical/real world input about hardware:
—) My opninion, FWIW.
Do steinberg products benefit at all from intel processors with more than 4 cores (8 threads)?
—) yes
Can cubase even take advantage of a 6 core (12 thread) or 8 core (16 thread) machine?
—) yes
Or is it plug-ins and soft instruments that would?
—) the plugins used should be able to handle multicore processing
Also, some of these machines can support 32, 64, and even 128GB of RAM. Would music production even come close to taking advantage of all that?
—) It depends on the overall balance of your setup. Oversized RAM configurations are only usefull when you need them. (i.e. you use a lot of sample players with gigabytes loaded in RAM)
What is a practical “more than enough” amount?
—) I think 16 gig is more then enough for 99% of the situations. But it really depends on what you want to load.
If you want very large setups with everything active, 16 gig is not enough. None of the systems i have being told of have more then 64 gig. There is a limit in how much memory a motherboard can handle and in most situations that is the limiting factor. And i think supercomputers like they do exist nowadays are overkill for a DAW-computer. 
I completely understand the idea of building more than you need in the hopes of longevity, and future compatibility/capability, but if I just plain don’t need it, and won’t need it in the foreseeable future, I wouldn’t mind spending some of this budget on gear.
—) just google around and look for pro-audio systems. Look what they offer, and this is most of the time configured for what musicians would need.
example: http://www.adkproaudio.com/choose2.asp
(with a horrible gramatical failure on their site for the moment (corre), but they are pro) 
—) there is also a method to use multiple computers in a network to spread the workload if you really want to go big.
example: http://www.viennaensemblepro.com/
(but there are other brands on the market too)
kind regards,
R.