Unmix song with extreme settings.... slow Zzzzzz

A PC with at least 16GB RAM, CPU doesn’t matter that much (as long as it has at least 4 cores and was produced in the last 4 years), and for GPU I would recommend (depending on your budget) a RTX 3060, or if you can afford it, a RTX 3090 / RTX 4090 which will give you maximum speed.
That being said, even a RTX 3060 will cut your processing time from 45 min to less than 10 min.