I just bought a ur22MKII, and Im having same issues with a Dell laptop, integrated Intel graphics, Win 10 64 bit, 8 gb ram. My previous interface was a cheap Samson usinG asio4ALL, but it worked fine. Now I cant watch youtube videos without repeated dropouts, and the dropouts also occur in Bias FX. The USB light blinks when the audio drops. Ive disabled everything I can, all power management, Speed boosts, etc. Tried all 3 USB ports. Tried old driver and new. Different USB cable. I cant disable my wifi, because i use it. And my internal sound card can play videos and music fine, so this one should at least be able to do that. Disappointed so far. I hope theres a solution,