UR22 no input or output signal anymore :(

Hi Everyone,

Been searching through these threads for answers but found no solutions.

Using Mac Mini 2018 256 GB version. Newest Logic Pro X, and UR22.
It was working fine up until yesterday when I plugged in a guitar and am getting zero input signal, no movement in channel strip and zero output through headphones.

Have tried a lot of the recommended troubleshooting: changing cables, testing cables, reinstalling drivers, reinstalling logic pro x, resetting NVRAM, SMC, Made sure MIDI Audio Devices is showing correctly, etc.

Only thing I can think of is I just updated from Catalina 10.15.15 to 10.15.16, has anyone else experiencing no signal at all (output and input) since update?