After a lot of dropouts, restarts and USB Error problems I tried a few workarounds, here’s what worked best.
USB A cable from PC to UR22c USB C input.
Set the Steinberg/Yamaha Control to USB 2
Set your DAW to run ASIO4ALL driver.
I have a 7.5 yr old HP laptop and I use the usb c port with the high speed setting and an older version of the Yamaha ASIO driver no problem with my ur22c. I am using elements 11. As far as driver updates I use the moto if it ain’t broken don’t fix it.