Just bought and installed the ur 816c, however there is no hardware option coming up on cubase 10.0.5 pro version. The Yamaha AADM Extension does load when i start up cubase. I cannot see the Yamah plugins in the insert folder too.
I use UR816c and Control Room at the same time. You need to use separate (free) “stereo out” in your audio connections. Also, if the track you are recording to is routed to the bus other than stereo out, you loose hardvare control tab in Cubase inspector. (I use Cubase 11 pro)