Hi @user450 , I too have Dorico 4.1.10.1082 and Mac OS 12.4 Monterey and all works perfectly. I recall Daniel saying that if you decide to uninstall/reinstall then make sure you make a copy of your Dorico folder first incase all your previous work is deleted. In iCloud I have a Dorico folder with a tiny little Dorico icon inside the folder symbol. If you have such a folder, back it up somewhere, along with any other folders you store your projects in.
Uninstalling/reinstalling may solve the problem.